BDBM50603678 CHEMBL5202351
SMILES CC(C)C[C@H](N)c1cc(C#N)c2cc(ccc2n1)-c1ccncc1
InChI Key InChIKey=FMNWOBLAZAYOSG-SFHVURJKSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 8 hits for monomerid = 50603678
Affinity DataIC50: 5.80nMAssay Description:Inhibition of recombinant human GST-Xa-tagged-AAK1 (30 to 330 residues) using (5-FAM)-Aha-KEEQSQITSQVTGQIGWR-NH2 as substrate incubated for 3 hrs in ...More data for this Ligand-Target Pair
Affinity DataIC50: 19nMAssay Description:Inhibition of full length human AAK1 expressed in HEK293F incubated for 3 hrs by Western blot analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 161nMAssay Description:Inhibition of BIKE (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+3nMAssay Description:Inhibition of MPSK1 (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 112nMAssay Description:Inhibition of GSK3beta (unknown origin)More data for this Ligand-Target Pair
TargetMAP kinase-interacting serine/threonine-protein kinase 1(Homo sapiens (Human))
Bristol Myers Squibb
Curated by ChEMBL
Bristol Myers Squibb
Curated by ChEMBL
Affinity DataIC50: 57nMAssay Description:Inhibition of MNK1 (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+3nMAssay Description:Inhibition of GAK (unknown origin)More data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase Chk1(Homo sapiens (Human))
Bristol Myers Squibb
Curated by ChEMBL
Bristol Myers Squibb
Curated by ChEMBL
Affinity DataIC50: 998nMAssay Description:Inhibition of CHK1 (unknown origin)More data for this Ligand-Target Pair