BDBM50604021 CHEMBL5207194
SMILES Cc1cc(ncc1-c1ccc(cc1)C1(COC1)C(=O)Nc1ccc(F)cc1)C1CC1
InChI Key InChIKey=ZBXAYRHDZBOZCA-UHFFFAOYSA-N
Data 3 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 3 hits for monomerid = 50604021
Affinity DataIC50: 2.30nMAssay Description:Inhibition of IDO1 in IFN gamma-stimulated human HeLa cells measured after 48 hrs by fluorescence based microplate reader assayMore data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Pharmaron Beijing
Curated by ChEMBL
Pharmaron Beijing
Curated by ChEMBL
Affinity DataIC50: 1.59E+7nMAssay Description:Inhibition of MK-499 binding to hERGMore data for this Ligand-Target Pair
Affinity DataIC50: 0.0800nMAssay Description:Inhibition of IDO1 in IFNgamma/LPS stimulated human whole blood assessed as unbound concentration using kynurenine/tryptophan as substrate preincubat...More data for this Ligand-Target Pair