BDBM50604877 CHEMBL5189912

SMILES CSc1ccc(cc1)C(Nc1ccccn1)c1c(C)[nH]c2ccccc12

InChI Key InChIKey=BULDSMXGVHSVEQ-UHFFFAOYSA-N

Data  3 KI  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50604877   

LigandPNGBDBM50604877(CHEMBL5189912)
Affinity DataKi:  2.90E+3nMAssay Description:Inhibition of Bfl-1/Bim (unknown origin) assessed as inhibition constant by fluorescence polarization assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetBcl-2-related protein A1(Homo sapiens (Human))
Yancheng Teachers University

Curated by ChEMBL
LigandPNGBDBM50604877(CHEMBL5189912)
Affinity DataKi:  2.90E+3nMAssay Description:Displacement of fluorescent-labeled BID-BH3 peptide from His-tagged human BFL-1 (1 to 151 residues) expressed in Escherichia coli BL21 (DE3) assessed...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetApoptosis regulator Bcl-2(Homo sapiens (Human))
Yancheng Teachers University

Curated by ChEMBL
LigandPNGBDBM50604877(CHEMBL5189912)
Affinity DataKi:  1.29E+4nMAssay Description:Displacement of fluorescent-labeled BID-BH3 peptide from human BCL-2 expressed in Escherichia coli BL21 (DE3) assessed as inhibition constant by fluo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
LigandPNGBDBM50604877(CHEMBL5189912)
Affinity DataIC50:  2.50E+3nMAssay Description:Inhibition of Bfl-1/Bim (unknown origin) incubated for 30 mins by TR-FRET assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
LigandPNGBDBM50604877(CHEMBL5189912)
Affinity DataIC50:  6.30E+3nMAssay Description:Inhibition of Bfl-1/Bim (unknown origin) by fluorescence polarization assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed