BDBM50605406 CHEMBL5190935
SMILES [H][C@@]1(CC[C@@]2([H])C3[C@@H](O)C[C@]4([H])C[C@H](O)CC[C@]4(C)[C@@]3([H])CC[C@]12C)[C@H](C)CCC(=O)N1CCC(CC1)Oc1ccc(cc1)B(O)O
InChI Key InChIKey=ZIFDOLGFKFUTEG-SRAOFPMWSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 9 hits for monomerid = 50605406
TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 2(Rattus norvegicus)
University Of Strathclyde
Curated by ChEMBL
University Of Strathclyde
Curated by ChEMBL
Affinity DataKi: 9nMAssay Description:Inhibition of rat ATX by Michaelis-Menten analysisMore data for this Ligand-Target Pair
TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 2(Rattus norvegicus)
University Of Strathclyde
Curated by ChEMBL
University Of Strathclyde
Curated by ChEMBL
Affinity DataIC50: 54nMAssay Description:Inhibition of rat ATX lysoPLD activity assessed as reduction in choline release using 14:0 LPC as substrate measured after 60 mins by HVA fluorescenc...More data for this Ligand-Target Pair
TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 2(Rattus norvegicus)
University Of Strathclyde
Curated by ChEMBL
University Of Strathclyde
Curated by ChEMBL
Affinity DataIC50: 34nMAssay Description:Inhibition of rat ATX lysoPLD activity assessed as reduction in choline release using 16:0 LPC as substrate measured after 60 mins by HVA fluorescenc...More data for this Ligand-Target Pair
TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 2(Rattus norvegicus)
University Of Strathclyde
Curated by ChEMBL
University Of Strathclyde
Curated by ChEMBL
Affinity DataIC50: 29nMAssay Description:Inhibition of rat ATX lysoPLD activity assessed as reduction in choline release using 18:1 LPC as substrate measured after 60 mins by HVA fluorescenc...More data for this Ligand-Target Pair
TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 2(Homo sapiens (Human))
University Of Strathclyde
Curated by ChEMBL
University Of Strathclyde
Curated by ChEMBL
Affinity DataEC50: 186nMAssay Description:Inhibition of LPA-mediated ATX activation in human MDA-MB-231 cells assessed as reduction in cell migration incubated for 4 hrs in using18:1 LPC as s...More data for this Ligand-Target Pair
TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 2(Homo sapiens (Human))
University Of Strathclyde
Curated by ChEMBL
University Of Strathclyde
Curated by ChEMBL
Affinity DataEC50: 60nMAssay Description:Inhibition of LPA-mediated ATX activation in human BJeH cells assessed as AKT phosphorylation level incubated for 30 mins by Western blot analysisMore data for this Ligand-Target Pair
TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 2(Homo sapiens (Human))
University Of Strathclyde
Curated by ChEMBL
University Of Strathclyde
Curated by ChEMBL
Affinity DataEC50: 60nMAssay Description:Inhibition of LPA-mediated ATX activation in human BJeH cells assessed as ERK phosphorylation level incubated for 30 mins by Western blot analysisMore data for this Ligand-Target Pair
TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 2(Rattus norvegicus)
University Of Strathclyde
Curated by ChEMBL
University Of Strathclyde
Curated by ChEMBL
Affinity DataIC50: 30nMAssay Description:Inhibition of rat ATX lysoPLD activity using LPC as substrate assessed as reduction in choline release measured after 60 mins by HVA fluorescence bas...More data for this Ligand-Target Pair
TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 2(Rattus norvegicus)
University Of Strathclyde
Curated by ChEMBL
University Of Strathclyde
Curated by ChEMBL
Affinity DataIC50: 33nMAssay Description:Inhibition of rat ATX lysoPLD activity assessed as reduction in choline release using 20:0 LPC as substrate measured after 60 mins by HVA fluorescenc...More data for this Ligand-Target Pair