BDBM50606012 CHEMBL5087558

SMILES CC(C)(C)NC(=O)c1ccc-2cc1OCCOCCNc1ccn3ncc-2c3n1

InChI Key InChIKey=YCFFONJEHNSECY-UHFFFAOYSA-N

Data  7 IC50  1 Kd

PDB links: 1 PDB ID matches this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 50606012   

TargetSerine/threonine-protein kinase 17A(Homo sapiens (Human))
Goethe University Frankfurt

Curated by ChEMBL
LigandPNGBDBM50606012(CHEMBL5087558)
Affinity DataKd:  21nMAssay Description:Binding affinity to human N-terminal His-tagged/ TEV cleavage fused DRAK1 (39 to 369 residues) expressed in Escherichia coli by isothermal titration ...More data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase 17A(Homo sapiens (Human))
Goethe University Frankfurt

Curated by ChEMBL
LigandPNGBDBM50606012(CHEMBL5087558)
Affinity DataIC50:  49nMAssay Description:Inhibition of human N-terminal His-tagged/ TEV cleavage fused DRAK1 (39 to 369 residues) expressed in Escherichia coli using KKLNRTLSFAEPG peptide as...More data for this Ligand-Target Pair
TargetCasein kinase II subunit alpha(Homo sapiens (Human))
Goethe University Frankfurt

Curated by ChEMBL
LigandPNGBDBM50606012(CHEMBL5087558)
Affinity DataIC50:  950nMAssay Description:Inhibition of human CK2alpha1 using RRRDDDSDDD peptide as substrate in presence of [gamma-33P]ATP by radiometric based scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetSerine/threonine-protein kinase 17B(Homo sapiens (Human))
Goethe University Frankfurt

Curated by ChEMBL
LigandPNGBDBM50606012(CHEMBL5087558)
Affinity DataIC50:  8.40E+3nMAssay Description:Inhibition of DRAK2 (unknown origin) transfected in HEK293T cells using NanoBRET NanoGlo as substrate incubated for 2 hrs by NanoBRET assayMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetCasein kinase II subunit alpha(Homo sapiens (Human))
Goethe University Frankfurt

Curated by ChEMBL
LigandPNGBDBM50606012(CHEMBL5087558)
Affinity DataIC50:  3.40E+4nMAssay Description:Inhibition of CK2alpha1(unknown origin) transfected in HEK293T cells using NanoBRET NanoGlo as substrate incubated for 2 hrs by NanoBRET assayMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetCyclin-G-associated kinase(Homo sapiens (Human))
Goethe University Frankfurt

Curated by ChEMBL
LigandPNGBDBM50606012(CHEMBL5087558)
Affinity DataIC50:  2.40E+4nMAssay Description:Inhibition of GAK (unknown origin) transfected in HEK293T cells using NanoBRET NanoGlo as substrate incubated for 2 hrs by NanoBRET assayMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetBMP-2-inducible protein kinase(Homo sapiens (Human))
Goethe University Frankfurt

Curated by ChEMBL
LigandPNGBDBM50606012(CHEMBL5087558)
Affinity DataIC50:  8.00E+3nMAssay Description:Inhibition of BIKE (unknown origin) transfected in HEK293T cells using NanoBRET NanoGlo as substrate incubated for 2 hrs by NanoBRET assayMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetSerine/threonine-protein kinase 17A(Homo sapiens (Human))
Goethe University Frankfurt

Curated by ChEMBL
LigandPNGBDBM50606012(CHEMBL5087558)
Affinity DataIC50:  182nMAssay Description:Inhibition of human N-terminal His-tagged/ TEV cleavage fused DRAK1 (39 to 369 residues) transfected in HEK293T cells using NanoBRET NanoGlo as subst...More data for this Ligand-Target Pair