BDBM50606981 CHEMBL5220330

SMILES [#8]-c1c(Cl)cc(cc1Cl)-c1ccc(-[#8]-[#6]-c2ccccc2)c(\[#6]=[#6]-2\[#6](=O)-[#7]-[#6](=S)-[#7]-[#6]-2=O)c1

InChI Key InChIKey=IELWXSVQTPMCEM-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50606981   

TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Peking Union Medical College And Chinese Academy Of Medical Sciences

Curated by ChEMBL
LigandPNGBDBM50606981(CHEMBL5220330)
Affinity DataIC50:  2.73E+4nMAssay Description:Inhibition of recombinant human PTP1B using pNPP as substrate preincubated for 5 mins followed by substrate addition assessed as reduction in p-nitro...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetTriple specificity protein phosphatase PtpB()
Peking Union Medical College And Chinese Academy Of Medical Sciences

Curated by ChEMBL
LigandPNGBDBM50606981(CHEMBL5220330)
Affinity DataIC50:  3.81E+3nMAssay Description:Inhibition of recombinant Mycobacterium tuberculosis H37Rv MptpB using pNPP as substrate incubated for 10 mins and measured by spectrophotometric met...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed