BDBM50607111 CHEMBL5218807
SMILES Cc1c(Br)cc(NC(=O)NS(O)(=O)=O)cc1Br
InChI Key InChIKey=XBWKZLBEUSPLFY-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 27 hits for monomerid = 50607111
TargetLow molecular weight phosphotyrosine protein phosphatase(Homo sapiens (Human))
Eli Lilly
Curated by ChEMBL
Eli Lilly
Curated by ChEMBL
Affinity DataKi: 1.20nMAssay Description:Competitive inhibition of LMW-PTP (unknown origin) assessed as inhibition constant by Lineweaver-Burk plot analysisMore data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 7(Homo sapiens (Human))
Eli Lilly
Curated by ChEMBL
Eli Lilly
Curated by ChEMBL
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of HePTP (unknown origin)More data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 22(Homo sapiens (Human))
Eli Lilly
Curated by ChEMBL
Eli Lilly
Curated by ChEMBL
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of LYP (unknown origin)More data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 6(Homo sapiens (Human))
Eli Lilly
Curated by ChEMBL
Eli Lilly
Curated by ChEMBL
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of SHP1 (unknown origin)More data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 2(Homo sapiens (Human))
Eli Lilly
Curated by ChEMBL
Eli Lilly
Curated by ChEMBL
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of TC-PTP (unknown origin)More data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 11(Homo sapiens (Human))
Eli Lilly
Curated by ChEMBL
Eli Lilly
Curated by ChEMBL
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of SHP2 (unknown origin)More data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Eli Lilly
Curated by ChEMBL
Eli Lilly
Curated by ChEMBL
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of PTP1B (unknown origin)More data for this Ligand-Target Pair
TargetLow molecular weight phosphotyrosine protein phosphatase(Mus musculus)
Eli Lilly
Curated by ChEMBL
Eli Lilly
Curated by ChEMBL
Affinity DataIC50: 3nMAssay Description:Inhibition of N-terminal His-tagged full length mouse LMW-PTP expressed in Escherichia coli BL21(DE3) by SDS PAGE based mass spectrometry analysisMore data for this Ligand-Target Pair
TargetLow molecular weight phosphotyrosine protein phosphatase(Homo sapiens (Human))
Eli Lilly
Curated by ChEMBL
Eli Lilly
Curated by ChEMBL
Affinity DataIC50: 4nMAssay Description:Inhibition of His-tagged human LMW-PTP expressed in Escherichia coli BL21 using pNPP as substrate incubated for 10 mins by microplate reader based sp...More data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 12(Homo sapiens (Human))
Eli Lilly
Curated by ChEMBL
Eli Lilly
Curated by ChEMBL
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of PEST(unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of CD45 (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of LAR(unknown origin)More data for this Ligand-Target Pair
TargetReceptor-type tyrosine-protein phosphatase alpha(Homo sapiens (Human))
Eli Lilly
Curated by ChEMBL
Eli Lilly
Curated by ChEMBL
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of PTPalpha (unknown origin)More data for this Ligand-Target Pair
TargetReceptor-type tyrosine-protein phosphatase beta(Homo sapiens (Human))
Eli Lilly
Curated by ChEMBL
Eli Lilly
Curated by ChEMBL
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of PTPbeta (unknown origin)More data for this Ligand-Target Pair
TargetReceptor-type tyrosine-protein phosphatase gamma(Homo sapiens (Human))
Eli Lilly
Curated by ChEMBL
Eli Lilly
Curated by ChEMBL
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of PTPgamma (unknown origin)More data for this Ligand-Target Pair
TargetReceptor-type tyrosine-protein phosphatase epsilon(Homo sapiens (Human))
Eli Lilly
Curated by ChEMBL
Eli Lilly
Curated by ChEMBL
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of PTPepsilon (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of PTPsigma (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of PTPmu (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of MKP3 (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of VHR (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of VHZ (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of CDC14A (unknown origin)More data for this Ligand-Target Pair
TargetRNA polymerase II subunit A C-terminal domain phosphatase SSU72(Homo sapiens (Human))
Eli Lilly
Curated by ChEMBL
Eli Lilly
Curated by ChEMBL
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of SSU72 (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of PP5 (unknown origin)More data for this Ligand-Target Pair
TargetLow molecular weight phosphotyrosine protein phosphatase(Rattus norvegicus)
Eli Lilly
Curated by ChEMBL
Eli Lilly
Curated by ChEMBL
Affinity DataIC50: 3nMAssay Description:Inhibition of N-terminal His-tagged full length rat LMW-PTP expressed in Escherichia coli BL21(DE3)More data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 13(Homo sapiens (Human))
Eli Lilly
Curated by ChEMBL
Eli Lilly
Curated by ChEMBL
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of FAP-1(unknown origin)More data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 3(Homo sapiens (Human))
Eli Lilly
Curated by ChEMBL
Eli Lilly
Curated by ChEMBL
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of PTPH1 (unknown origin)More data for this Ligand-Target Pair