BDBM50607585 CHEMBL5219512
SMILES Oc1ccc(NC(=O)[C@H]2CCCN2C(=O)C2(CCCC2)c2cccc(Cl)c2)cc1
InChI Key InChIKey=VGLLUDVOHKEEAB-HXUWFJFHSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 50607585
TargetCREB-binding protein/Histone acetyltransferase p300(Homo sapiens (Human))
Glaxosmithkline
Curated by ChEMBL
Glaxosmithkline
Curated by ChEMBL
Affinity DataEC50: 251nMAssay Description:Inhibition of CBP/p300 in human COLO 320HSR cells assessed as reduction of C-myc levels measured after 24 hrs by HTRF assayMore data for this Ligand-Target Pair
Affinity DataIC50: 0.631nMAssay Description:Inhibition of full-length P300 (unknown origin) using ARTKQTARKSTGGKAPRKQLAGG-K(Biotin)-amide as substrate preincubated for 60 mins followed by subst...More data for this Ligand-Target Pair