BDBM50607645 CHEMBL5219034::US11718589, Compound 66b

SMILES COc1nccc2cc(ccc12)-c1cnc2ccc(cc2n1)C(=O)N1CCCCC1

InChI Key InChIKey=WVPWRVGMZDPNJF-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50607645   

Target15-hydroxyprostaglandin dehydrogenase [NAD(+)](Homo sapiens (Human))
Ut Southwestern Medical Center

Curated by ChEMBL
LigandPNGBDBM50607645(CHEMBL5219034 | US11718589, Compound 66b)
Affinity DataIC50:  4nMAssay Description:Inhibition of 15-PGDH (unknown origin) using NAD as substrate measured for 3.5 minsMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
Target15-hydroxyprostaglandin dehydrogenase [NAD(+)](Homo sapiens (Human))
Ut Southwestern Medical Center

Curated by ChEMBL
LigandPNGBDBM50607645(CHEMBL5219034 | US11718589, Compound 66b)
Affinity DataIC50:  12nMAssay Description:This Example provides data on two groups (Table 1 and Table 2) of structural analogues of identified 15-PGDH inhibitors. Data provided is the IC50 of...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent