BDBM50607648 CHEMBL5220884::US11718589, Compound 78b

SMILES Cn1ccc2cc(ccc2c1=O)-c1cnc2ccc(cc2n1)C(=O)N1CCCCC1

InChI Key InChIKey=URHPFANOQLIROT-UHFFFAOYSA-N

Data  5 IC50

PDB links: 1 PDB ID matches this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50607648   

Target15-hydroxyprostaglandin dehydrogenase [NAD(+)](Homo sapiens (Human))
Case Western Reserve University

US Patent
LigandPNGBDBM50607648(CHEMBL5220884 | US11718589, Compound 78b)
Affinity DataIC50:  3nMAssay Description:This Example provides data on two groups (Table 1 and Table 2) of structural analogues of identified 15-PGDH inhibitors. Data provided is the IC50 of...More data for this Ligand-Target Pair
Target15-hydroxyprostaglandin dehydrogenase [NAD(+)](Homo sapiens (Human))
Case Western Reserve University

US Patent
LigandPNGBDBM50607648(CHEMBL5220884 | US11718589, Compound 78b)
Affinity DataIC50:  3nMAssay Description:Inhibition of 15-PGDH (unknown origin) using NAD as substrate measured for 3.5 minsMore data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Homo sapiens (Human))
Ut Southwestern Medical Center

Curated by ChEMBL
LigandPNGBDBM50607648(CHEMBL5220884 | US11718589, Compound 78b)
Affinity DataIC50:  1.20E+3nMAssay Description:Inhibition of PDE4D2 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
Ut Southwestern Medical Center

Curated by ChEMBL
LigandPNGBDBM50607648(CHEMBL5220884 | US11718589, Compound 78b)
Affinity DataIC50:  5.40E+3nMAssay Description:Inhibition of acetylcholinesterase (unknown origin)More data for this Ligand-Target Pair
In DepthDetails PubMed
Target15-hydroxyprostaglandin dehydrogenase [NAD(+)](Homo sapiens (Human))
Case Western Reserve University

US Patent
LigandPNGBDBM50607648(CHEMBL5220884 | US11718589, Compound 78b)
Affinity DataIC50:  4.00E+3nMAssay Description:Inhibition of 15-PGDH (unknown origin) using PGE2 as substrateMore data for this Ligand-Target Pair