BDBM50607648 CHEMBL5220884::US11718589, Compound 78b
SMILES Cn1ccc2cc(ccc2c1=O)-c1cnc2ccc(cc2n1)C(=O)N1CCCCC1
InChI Key InChIKey=URHPFANOQLIROT-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 5 hits for monomerid = 50607648
Target15-hydroxyprostaglandin dehydrogenase [NAD(+)](Homo sapiens (Human))
Case Western Reserve University
US Patent
Case Western Reserve University
US Patent
Affinity DataIC50: 3nMAssay Description:This Example provides data on two groups (Table 1 and Table 2) of structural analogues of identified 15-PGDH inhibitors. Data provided is the IC50 of...More data for this Ligand-Target Pair
Target15-hydroxyprostaglandin dehydrogenase [NAD(+)](Homo sapiens (Human))
Case Western Reserve University
US Patent
Case Western Reserve University
US Patent
Affinity DataIC50: 3nMAssay Description:Inhibition of 15-PGDH (unknown origin) using NAD as substrate measured for 3.5 minsMore data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Homo sapiens (Human))
Ut Southwestern Medical Center
Curated by ChEMBL
Ut Southwestern Medical Center
Curated by ChEMBL
Affinity DataIC50: 1.20E+3nMAssay Description:Inhibition of PDE4D2 (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 5.40E+3nMAssay Description:Inhibition of acetylcholinesterase (unknown origin)More data for this Ligand-Target Pair
Target15-hydroxyprostaglandin dehydrogenase [NAD(+)](Homo sapiens (Human))
Case Western Reserve University
US Patent
Case Western Reserve University
US Patent
Affinity DataIC50: 4.00E+3nMAssay Description:Inhibition of 15-PGDH (unknown origin) using PGE2 as substrateMore data for this Ligand-Target Pair