BDBM50610152 CHEMBL5268912

SMILES COCCOCc1cc(F)ccc1CNC(=O)c1cc(C(=O)Nc2ccc(cc2C)C(F)(F)F)c(Cl)cc1F

InChI Key InChIKey=PVTRYMNBUCBYEB-UHFFFAOYSA-N

Data  1 IC50  1 EC50

PDB links: 1 PDB ID matches this monomer.

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50610152   

TargetPeroxisome proliferator-activated receptor gamma(Homo sapiens (Human))TBA

LigandBDBM50610152(CHEMBL5268912)Copy SMILESCopy InChI

Affinity DataIC50:  7.40nMAssay Description:Inverse agonist activity at human PPARgamma in human RT112/84 transfected with NLuc-fused FABP4 assessed as reduction in PPARgamma transactivation in...More data for this Ligand-Target Pair

Target InfoPDBMMDBNCI pathwayReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADDrugBankantibodypediaGoogleScholar

Ligand InfoPC cidPC sidPDB

In DepthDetails PubMedPDB3D Structure (crystal)
Copy BDB DOI

TargetPeroxisome proliferator-activated receptor gamma(Homo sapiens (Human))TBA

LigandBDBM50610152(CHEMBL5268912)Copy SMILESCopy InChI

Affinity DataEC50:  31nMAssay Description:Inverse agonist activity at GST tagged human PPARgamma LBD (231 to 505 residues) expressed in Escherichia coli BL21(DE3) assessed as recruitment of f...More data for this Ligand-Target Pair

Target InfoPDBMMDBNCI pathwayReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADDrugBankantibodypediaGoogleScholar

Ligand InfoPC cidPC sidPDB

In DepthDetails PubMedPDB3D Structure (crystal)
Copy BDB DOI