BDBM50611023 CHEMBL5273876

SMILES CC[C@@H](Nc1c(C#N)c(nc2cnccc12)-c1ccc(cc1)-c1ccccc1OC)C(N)=O

InChI Key InChIKey=BKGMBRCBFNCTSH-OAQYLSRUSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50611023   

LigandPNGBDBM50611023(CHEMBL5273876)
Affinity DataIC50:  42nMAssay Description:Inhibition of recombinant full length His-tagged PIP4K2A (unknown origin) expressed in sf21 cells assessed as reduction in ADP production preincubate...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails PubMed
LigandPNGBDBM50611023(CHEMBL5273876)
Affinity DataIC50:  330nMAssay Description:Inhibition of recombinant full length His-tagged PIP4K2A (unknown origin) expressed in sf21 assessed as reduction in PI4,5P2 production preincubated ...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails PubMed
LigandPNGBDBM50611023(CHEMBL5273876)
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibition of human PIP4K2A in human THP-1 cells assessed as increase in Akt phosphorylation at Ser473 residue incubated for 2 hrs by HTRF assayMore data for this Ligand-Target Pair
Ligand Info
In DepthDetails PubMed
LigandPNGBDBM50611023(CHEMBL5273876)
Affinity DataIC50:  2.43E+3nMAssay Description:Inhibition of recombinant full length His-tagged PIP4K2A (unknown origin) expressed in sf21 assessed as reduction in PI4,5P2 production preincubated ...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails PubMed
LigandPNGBDBM50611023(CHEMBL5273876)
Affinity DataIC50:  280nMAssay Description:Inhibition of recombinant full length His-tagged PIP4K2A (unknown origin) expressed in sf21 cells assessed as reduction in ADP production preincubate...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails PubMed