BDBM50612195 CHEMBL5288931
SMILES CN1CCC(CC1)n1cc(Nc2nc(OC3(C)CC3)c3nc(c(F)cc3n2)-c2cnc(C)nc2)cn1
InChI Key InChIKey=SZURKEABSBIIMJ-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 9 hits for monomerid = 50612195
Affinity DataIC50: 3nMAssay Description:Inhibition of IRAK4 (unknown origin) in presence of ATP by enzymatic assayMore data for this Ligand-Target Pair
Ligand InfoPDB
Affinity DataIC50: 110nMAssay Description:Inhibition of IRAK4 (unknown origin) phosphorylation by cell based assayMore data for this Ligand-Target Pair
Ligand InfoPDB
Affinity DataIC50: 1.40E+3nMAssay Description:Inhibition of IRAK1 (unknown origin) in presence of 25 uM ATPMore data for this Ligand-Target Pair
Ligand InfoPDB
Affinity DataIC50: >8.00E+3nMAssay Description:Inhibition of BTK (unknown origin) in presence of 25 uM ATPMore data for this Ligand-Target Pair
Target InfoPDBMMDBNCI pathwayReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADDrugBankantibodypediaGoogleScholar
UniProtKB/SwissProt
B.MOADDrugBankantibodypediaGoogleScholar
Ligand InfoPDB
Affinity DataIC50: 270nMAssay Description:Inhibition of TRKC (unknown origin) in presence of 50 uM ATPMore data for this Ligand-Target Pair
Ligand InfoPDB
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform(Homo sapiens (Human))TBA
Affinity DataIC50: 53nMAssay Description:Inhibition of PI3Kdelta (unknown origin) in presence of 75 uM ATPMore data for this Ligand-Target Pair
Target InfoPDBMMDBNCI pathwayReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADDrugBankantibodypediaGoogleScholar
UniProtKB/SwissProt
B.MOADDrugBankantibodypediaGoogleScholar
Ligand InfoPDB
Affinity DataIC50: 270nMAssay Description:Inhibition of TRKA (unknown origin) in presence of 400 uM ATPMore data for this Ligand-Target Pair
Ligand InfoPDB
Affinity DataIC50: 760nMAssay Description:Inhibition of TRKB (unknown origin) in presence of 25 uM ATPMore data for this Ligand-Target Pair
Ligand InfoPDB
Affinity DataIC50: >9.00E+3nMAssay Description:Inhibition of FLT3 (unknown origin) in presence of 600 uM ATPMore data for this Ligand-Target Pair
Target InfoPDBNCI pathwayReactome pathway
UniProtKB/SwissProt
B.MOADDrugBankantibodypediaGoogleScholar
UniProtKB/SwissProt
B.MOADDrugBankantibodypediaGoogleScholar
Ligand InfoPDB