BDBM50612703 CHEMBL5269456

SMILES CCN(CC)c1ccc(\C=C2\N(C)C(=S)N(C2=O)c2ccccc2)cc1

InChI Key InChIKey=GTSMAEYGRDFLDK-XDJHFCHBSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50612703   

TargetCytochrome b-245 heavy chain(Homo sapiens (Human))TBA
LigandPNGBDBM50612703(CHEMBL5269456)
Affinity DataIC50:  1.96E+3nMAssay Description:Inhibition of human NOX2 assessed as reduction in ROS production using lucigenin as substrate in presence of NADPH by chemiluminescence based micropl...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails PubMed
TargetNADPH oxidase 4(Homo sapiens (Human))TBA
LigandPNGBDBM50612703(CHEMBL5269456)
Affinity DataIC50:  1.74E+3nMAssay Description:Inhibition of human NOX4 assessed as reduction in ROS production using lucigenin as substrate in presence of NADPH by chemiluminescence based micropl...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails PubMed