BDBM507697 (R)-5-(6-(3- cyanopyrrolo[1,2- b]pyridazin-7-yl)-4- (isopropylamino)pyridin- 3-yl)-N-(2-fluoro-3- hydroxy-3- methylbutyl)-1,3,4- thiadiazole-2- carboxamide::US11046686, Example 14

SMILES CC(C)Nc1cc(ncc1-c1nnc(s1)C(=O)NCC(F)C(C)(C)O)-c1ccc2cc(cnn12)C#N

InChI Key InChIKey=KVVGKLQIJBKDRV-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 507697   

TargetInterleukin-1 receptor-associated kinase 4(Homo sapiens (Human))
Gilead Sciences

US Patent
LigandPNGBDBM507697((R)-5-(6-(3- cyanopyrrolo[1,2- b]pyridazin-7-yl)-4...)
Affinity DataIC50: <1nMAssay Description:IRAK4 enzyme (Carna Biosciences, Chuo-ku, Kobe, Japan) activity was measured by detecting phosphorylated peptide substrate formation using an antibod...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent