BDBM507702 N-(5-(6-(3- cyanopyrrolo[1,2- b]pyridazin-7-yl)-4- (isopropylamino)pyridin- 3-yl)-1,3,4- thiadiazol-2- yl)acetamide::US11046686, Example 19::US11702414, Example 19

SMILES CC(C)Nc1cc(ncc1-c1nnc(NC(C)=O)s1)-c1ccc2cc(cnn12)C#N

InChI Key InChIKey=OECIDEBQBSYPOC-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 507702   

TargetInterleukin-1 receptor-associated kinase 4(Homo sapiens (Human))
Gilead Sciences

US Patent
LigandPNGBDBM507702(N-(5-(6-(3- cyanopyrrolo[1,2- b]pyridazin-7-yl)-4-...)
Affinity DataIC50:  1nMAssay Description:IRAK4 enzyme (Carna Biosciences, Chuo-ku, Kobe, Japan) activity was measured by detecting phosphorylated peptide substrate formation using an antibod...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetInterleukin-1 receptor-associated kinase 4(Homo sapiens (Human))
Gilead Sciences

US Patent
LigandPNGBDBM507702(N-(5-(6-(3- cyanopyrrolo[1,2- b]pyridazin-7-yl)-4-...)
Affinity DataIC50:  1nMAssay Description:IRAK4 enzyme (Carna Biosciences, Chuo-ku, Kobe, Japan) activity was measured by detecting phosphorylated peptide substrate formation using an antibod...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent