BDBM510150 N-(2,4-dichloro-6-(methoxy- methyl)benzyl)-8-hydroxy- 5,6,7,8-tetrahydro- quinoline-5-carboxamide::US11077100, Example 10::US11439633, Example 10

SMILES COCc1cc(Cl)cc(Cl)c1CNC(=O)C1CCC(O)c2ncccc12

InChI Key InChIKey=MYLGMABYQFRLOM-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 510150   

TargetP2X purinoceptor 7(Homo sapiens (Human))
Raqualia Pharma

US Patent
LigandPNGBDBM510150(N-(2,4-dichloro-6-(methoxy- methyl)benzyl)-8-hydro...)
Affinity DataIC50: <50nMAssay Description:The functional activity of compounds was determined by measuring changes in intracellular calcium concentration using a Ca2+-sensitive fluorescent dy...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetP2X purinoceptor 7(Homo sapiens (Human))
Raqualia Pharma

US Patent
LigandPNGBDBM510150(N-(2,4-dichloro-6-(methoxy- methyl)benzyl)-8-hydro...)
Affinity DataIC50: <50nMAssay Description:1. Wash each well with 80 microL of assay buffer (20 mM HEPES, 1×HBSS, pH 7.4 adjusted with NaOH) three times and leave 20 microL using plate washer,...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent