BDBM510162 N-(2,4-dichlorobenzyl)-5- fluoro-8-hydroxy-5,6,7,8- tetrahydroquinoline-5- carboxamide::US11077100, Example 22::US11439633, Example 22

SMILES OC1CCC(F)(C(=O)NCc2ccc(Cl)cc2Cl)c2cccnc12

InChI Key InChIKey=NUUQODROOFRFEQ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 510162   

TargetP2X purinoceptor 7(Homo sapiens (Human))
Raqualia Pharma

US Patent
LigandPNGBDBM510162(N-(2,4-dichlorobenzyl)-5- fluoro-8-hydroxy-5,6,7,8...)
Affinity DataIC50: <50nMAssay Description:The functional activity of compounds was determined by measuring changes in intracellular calcium concentration using a Ca2+-sensitive fluorescent dy...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetP2X purinoceptor 7(Homo sapiens (Human))
Raqualia Pharma

US Patent
LigandPNGBDBM510162(N-(2,4-dichlorobenzyl)-5- fluoro-8-hydroxy-5,6,7,8...)
Affinity DataIC50: <50nMAssay Description:1. Wash each well with 80 microL of assay buffer (20 mM HEPES, 1×HBSS, pH 7.4 adjusted with NaOH) three times and leave 20 microL using plate washer,...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent