BDBM510172 (2-amino-2-oxoethyl)-N- (2-chloro-3-(trifluoro- methyl)benzyl)-5,6,7,8-tetra- hydroquinoline-5- carboxamide::US11077100, Example 32::US11439633, Example 32

SMILES NC(=O)CC1CCC(C(=O)NCc2cccc(c2Cl)C(F)(F)F)c2cccnc12

InChI Key InChIKey=PQVAKMOKLDFQRI-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 510172   

TargetP2X purinoceptor 7(Homo sapiens (Human))
Raqualia Pharma

US Patent
LigandPNGBDBM510172((2-amino-2-oxoethyl)-N- (2-chloro-3-(trifluoro- me...)
Affinity DataIC50: <50nMAssay Description:The functional activity of compounds was determined by measuring changes in intracellular calcium concentration using a Ca2+-sensitive fluorescent dy...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetP2X purinoceptor 7(Homo sapiens (Human))
Raqualia Pharma

US Patent
LigandPNGBDBM510172((2-amino-2-oxoethyl)-N- (2-chloro-3-(trifluoro- me...)
Affinity DataIC50: <50nMAssay Description:1. Wash each well with 80 microL of assay buffer (20 mM HEPES, 1×HBSS, pH 7.4 adjusted with NaOH) three times and leave 20 microL using plate washer,...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent