BDBM510182 (5S*,8S*)-N-(2- chloro-4-fluoro- benzyl)-5-fluoro- 8-hydroxy-8- (methoxymethyl)- 5,6,7,8-tetra- hydroquinoline-5- carboxamide::US11077100, Example 42::US11439633, Example 42

SMILES COC[C@]1(O)CC[C@@](F)(C(=O)NCc2ccc(F)cc2Cl)c2cccnc12

InChI Key InChIKey=FQXHBNGITJBYKE-MOPGFXCFSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 510182   

TargetP2X purinoceptor 7(Homo sapiens (Human))
Raqualia Pharma

US Patent
LigandPNGBDBM510182((5S*,8S*)-N-(2- chloro-4-fluoro- benzyl)-5-fluoro-...)
Affinity DataIC50: <50nMAssay Description:The functional activity of compounds was determined by measuring changes in intracellular calcium concentration using a Ca2+-sensitive fluorescent dy...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetP2X purinoceptor 7(Homo sapiens (Human))
Raqualia Pharma

US Patent
LigandPNGBDBM510182((5S*,8S*)-N-(2- chloro-4-fluoro- benzyl)-5-fluoro-...)
Affinity DataIC50: <50nMAssay Description:1. Wash each well with 80 microL of assay buffer (20 mM HEPES, 1×HBSS, pH 7.4 adjusted with NaOH) three times and leave 20 microL using plate washer,...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent