BDBM510183 8-(aminomethyl)-N- (2,4-dichloro-6-meth- ylbenzyl)-8- hydroxy-5,6,7,8- tetrahydroquinoline- 5-carboxamide::US11077100, Example 43::US11439633, Example 43

SMILES Cc1cc(Cl)cc(Cl)c1CNC(=O)C1CCC(O)(CN)c2ncccc12

InChI Key InChIKey=VKURBHPIIDKNBF-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 510183   

TargetP2X purinoceptor 7(Homo sapiens (Human))
Raqualia Pharma

US Patent
LigandPNGBDBM510183(8-(aminomethyl)-N- (2,4-dichloro-6-meth- ylbenzyl)...)
Affinity DataIC50: <50nMAssay Description:The functional activity of compounds was determined by measuring changes in intracellular calcium concentration using a Ca2+-sensitive fluorescent dy...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetP2X purinoceptor 7(Homo sapiens (Human))
Raqualia Pharma

US Patent
LigandPNGBDBM510183(8-(aminomethyl)-N- (2,4-dichloro-6-meth- ylbenzyl)...)
Affinity DataIC50: <50nMAssay Description:1. Wash each well with 80 microL of assay buffer (20 mM HEPES, 1×HBSS, pH 7.4 adjusted with NaOH) three times and leave 20 microL using plate washer,...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent