BDBM510197 (5S*,8R*)-N-(2- chloro-4- fluorobenzyl)-5-fluoro- 8-hydroxy-8-(((2- hydroxyethyl)(meth- yl)amino) methyl)-5,6,7,8- tetrahydroquinoline-5- carboxamide::US11077100, Example 57::US11439633, Example 57

SMILES CN(CCO)C[C@]1(O)CC[C@@](F)(C(=O)NCc2ccc(F)cc2Cl)c2cccnc12

InChI Key InChIKey=OBEJTMVFHCHSQA-RTWAWAEBSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 510197   

TargetP2X purinoceptor 7(Homo sapiens (Human))
Raqualia Pharma

US Patent
LigandPNGBDBM510197((5S*,8R*)-N-(2- chloro-4- fluorobenzyl)-5-fluoro- ...)
Affinity DataIC50: <50nMAssay Description:The functional activity of compounds was determined by measuring changes in intracellular calcium concentration using a Ca2+-sensitive fluorescent dy...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetP2X purinoceptor 7(Homo sapiens (Human))
Raqualia Pharma

US Patent
LigandPNGBDBM510197((5S*,8R*)-N-(2- chloro-4- fluorobenzyl)-5-fluoro- ...)
Affinity DataIC50: <50nMAssay Description:1. Wash each well with 80 microL of assay buffer (20 mM HEPES, 1×HBSS, pH 7.4 adjusted with NaOH) three times and leave 20 microL using plate washer,...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent