BDBM510845 4-({(aR)-6-[7- cyclopropyl-6-(2- hydroxy-2- methylpropoxy)pyrazolo [1,5-a]pyridine-3- amido]spiro[3.3] heptan-2-yl}oxy)-2- methyl-1,3-thiazole- 5-carboxamide::US11078197, Example 22::US11673886, Example 22
SMILES Cc1nc(O[C@H]2C[C@@]3(C[C@@H](C3)NC(=O)c3cnn4c(C5CC5)c(OCC(C)(C)O)ccc34)C2)c(s1)C(N)=O
InChI Key InChIKey=LVGNYMQYXJDHFS-FXUCQVAHSA-N
Data 2 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 510845
Affinity DataIC50: 7nMAssay Description:The effectiveness of compounds of the present invention as ROCK inhibitors can be determined in a 30 μL assay containing 20 mM HEPES, pH 7.5, 20...More data for this Ligand-Target Pair
Affinity DataIC50: 7.00E+3nMAssay Description:The effectiveness of compounds of the present invention as ROCK inhibitors can be determined in a 30 μL assay containing 20 mM HEPES, pH 7.5, 20...More data for this Ligand-Target Pair