BDBM510954 1-(difluoromethyl)-6-(2- hydroxy-2- methylpropoxy)-N-[(4s)-6- ({3-carbamoyl-7- methylpyrazolo[1,5- a]pyridin-2- yl}oxy)spiro[3.3]heptan-2- yl]-1H-indazole-3- carboxamide::US11078197, Example 133::US11673886, Example 133
SMILES Cc1cccc2c(C(N)=O)c(O[C@H]3C[C@@]4(C[C@@H](C4)NC(=O)c4nn(C(F)F)c5cc(OCC(C)(C)O)ccc45)C3)nn12
InChI Key InChIKey=NRARBUYYXAEABB-ZVXFEBSPSA-N
Data 2 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 510954
Affinity DataIC50: 20.2nMAssay Description:The effectiveness of compounds of the present invention as ROCK inhibitors can be determined in a 30 μL assay containing 20 mM HEPES, pH 7.5, 20...More data for this Ligand-Target Pair
Affinity DataIC50: 2.02E+4nMAssay Description:The effectiveness of compounds of the present invention as ROCK inhibitors can be determined in a 30 μL assay containing 20 mM HEPES, pH 7.5, 20...More data for this Ligand-Target Pair