BDBM510989 (S)-5-(4- Aminoimidazo[2,1- f][1,2,4]triazin-7- yl)-2-(1- cyclopropylethyl) isoindolin-1-one::US11078204, Ex. No. 6

SMILES C[C@@H](C1CC1)N1Cc2cc(ccc2C1=O)-c1cnc2c(N)ncnn12

InChI Key InChIKey=UVCQBOZOFBRRSN-JTQLQIEISA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 510989   

LigandPNGBDBM510989((S)-5-(4- Aminoimidazo[2,1- f][1,2,4]triazin-7- yl...)
Affinity DataIC50: >2.00E+3nMAssay Description:The kinase reaction was conducted in polystyrene 384-well Greiner Bio-one white plate from Thermo Fisher Scientific in a final volume of 25 ??L. Inhi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
LigandPNGBDBM510989((S)-5-(4- Aminoimidazo[2,1- f][1,2,4]triazin-7- yl...)
Affinity DataIC50: <100nMAssay Description:The kinase reaction was conducted in polystyrene 384-well Greiner Bio-one white plate from Thermo Fisher Scientific in a final volume of 25 ??L. Inhi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent