BDBM511014 (S)-8-Amino-N- (bicyclo[1.1.1]pentan- 1-yl)-3-(2-(1- cyclopropylethyl)-7-::US11078204, Ex. No. 29b
SMILES CC(NC(=O)c1cn2c(cnc2c(N)n1)-c1cc2CN([C@@H](C)C3CC3)C(=O)c2c(c1)S(C)(=O)=O)NC12CC(C1)C2
InChI Key InChIKey=MKMUTOPVMSPUBU-VFRZZIAPSA-N
Data 2 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 511014
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform(Homo sapiens (Human))
Incyte
US Patent
Incyte
US Patent
Affinity DataIC50: <500nMAssay Description:The kinase reaction was conducted in polystyrene 384-well Greiner Bio-one white plate from Thermo Fisher Scientific in a final volume of 25 ??L. Inhi...More data for this Ligand-Target Pair
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform(Homo sapiens (Human))
Incyte
US Patent
Incyte
US Patent
Affinity DataIC50: <100nMAssay Description:The kinase reaction was conducted in polystyrene 384-well Greiner Bio-one white plate from Thermo Fisher Scientific in a final volume of 25 ??L. Inhi...More data for this Ligand-Target Pair