BDBM511018 (S)-8-Amino-3-(2-(1-cyclopropylethyl)- 1-oxoisoindolin-5-yl)-N-(3- hydroxycyclobutyl)imidazo[1,2- a]pyrazine-6-carboxamide, trifluoroacetate salt (mixture of two::US11078204, Ex. No. 31
SMILES C[C@@H](C1CC1)N1Cc2cc(ccc2C1=O)-c1cnc2c(N)nc(cn12)C(=O)NC1CC(O)C1
InChI Key InChIKey=JUMJBWJHOTUPQR-CDEQTRAXSA-N
Data 2 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 511018
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform(Homo sapiens (Human))
Incyte
US Patent
Incyte
US Patent
Affinity DataIC50: >2.00E+3nMAssay Description:The kinase reaction was conducted in polystyrene 384-well Greiner Bio-one white plate from Thermo Fisher Scientific in a final volume of 25 ??L. Inhi...More data for this Ligand-Target Pair
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform(Homo sapiens (Human))
Incyte
US Patent
Incyte
US Patent
Affinity DataIC50: <100nMAssay Description:The kinase reaction was conducted in polystyrene 384-well Greiner Bio-one white plate from Thermo Fisher Scientific in a final volume of 25 ??L. Inhi...More data for this Ligand-Target Pair