BDBM511024 (S)-5-(8-Amino-6-(5- methyl-1H-pyrazol-4- yl)imidazo[1,2-a]pyrazin- 3-yl)-2-(1- cyclopropylethyl)-7- (methylsulfonyl)isoindolin- 1-one, trifluoroacetate::US11078204, Ex. No. 37

SMILES C[C@@H](C1CC1)N1Cc2cc(cc(c2C1=O)S(C)(=O)=O)-c1cnc2c(N)nc(cn12)-c1cn[nH]c1C

InChI Key InChIKey=CDVRWQCLYHNSJM-ZDUSSCGKSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 511024   

LigandPNGBDBM511024((S)-5-(8-Amino-6-(5- methyl-1H-pyrazol-4- yl)imida...)
Affinity DataIC50: <500nMAssay Description:The kinase reaction was conducted in polystyrene 384-well Greiner Bio-one white plate from Thermo Fisher Scientific in a final volume of 25 ??L. Inhi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
LigandPNGBDBM511024((S)-5-(8-Amino-6-(5- methyl-1H-pyrazol-4- yl)imida...)
Affinity DataIC50: <100nMAssay Description:The kinase reaction was conducted in polystyrene 384-well Greiner Bio-one white plate from Thermo Fisher Scientific in a final volume of 25 ??L. Inhi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent