BDBM511316 3-Cyclopropyl-N-methyl-1-(3-(6-(methylcarbamoyl)pyridin-3-yl)isoquinolin-8-yl)-5,6-dihydroimidazo[1,5-a]pyrazine-7(8H)-carboxamide::US11058688, Example 17

SMILES CNC(=O)N1CCn2c(C1)c(nc2C1CC1)-c1cccc2cc(ncc12)-c1ccc(nc1)C(=O)NC

InChI Key InChIKey=QCZMBPQHUBPYSH-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 511316   

TargetBromodomain-containing protein 4 [49-170](Homo sapiens (Human))
Board of Regents, The University of Texas System

US Patent
LigandPNGBDBM511316(3-Cyclopropyl-N-methyl-1-(3-(6-(methylcarbamoyl)py...)
Affinity DataIC50:  5.09E+3nMAssay Description:The binding of 2.5 nM of BRD4(49-170) to 10 nM biotin-H4(1-21) Ac-K5/8/12/16 (AnaSpec. 64989) was assessed following the same procedure described for...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCREB-binding protein [1081-1197](Homo sapiens (Human))
Board of Regents, The University of Texas System

US Patent
LigandPNGBDBM511316(3-Cyclopropyl-N-methyl-1-(3-(6-(methylcarbamoyl)py...)
Affinity DataIC50:  1nMAssay Description:5 nM GST-CBP(1081-1197) and 20 nM biotin-H4(1-21) Ac-K5/8/12/16 (AnaSpec. 64989) were incubated with varying concentrations of CBP inhibitors in 15 &...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent