BDBM511356 N-methyl-1-(3-(6- (methylcarbamoyl)pyridin- 3-yl)isoquinolin-8-yl)-3- (tetrahydro-2H-pyran-4- yl)-5,6- dihydroimidazo[1,5- a]pyrazine-7(8H)- carboxamide::US11058688, Example 57
SMILES CNC(=O)N1CCn2c(C1)c(nc2C1CCOCC1)-c1cccc2cc(ncc12)-c1ccc(nc1)C(=O)NC
InChI Key InChIKey=CJGWAIGHWOPMFD-UHFFFAOYSA-N
Data 2 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 511356
TargetBromodomain-containing protein 4 [49-170](Homo sapiens (Human))
Board of Regents, The University of Texas System
US Patent
Board of Regents, The University of Texas System
US Patent
Affinity DataIC50: 5.97E+3nMAssay Description:The binding of 2.5 nM of BRD4(49-170) to 10 nM biotin-H4(1-21) Ac-K5/8/12/16 (AnaSpec. 64989) was assessed following the same procedure described for...More data for this Ligand-Target Pair
TargetCREB-binding protein [1081-1197](Homo sapiens (Human))
Board of Regents, The University of Texas System
US Patent
Board of Regents, The University of Texas System
US Patent
Affinity DataIC50: 1nMAssay Description:5 nM GST-CBP(1081-1197) and 20 nM biotin-H4(1-21) Ac-K5/8/12/16 (AnaSpec. 64989) were incubated with varying concentrations of CBP inhibitors in 15 &...More data for this Ligand-Target Pair