BDBM511377 3-(4,4- difluorocyclohexyl)-N- methyl-1-(2-(1-methyl- 1H-pyrazol-4-yl)-3- (trifluoromethyl)quinolin- 5-yl)-5,6- dihydroimidazo[1,5- a]pyrazine-7(8H)- carboxamide::US11058688, Example 78
SMILES CNC(=O)N1CCn2c(C1)c(nc2C1CCC(F)(F)CC1)-c1cccc2nc(-c3cnn(C)c3)c(cc12)C(F)(F)F
InChI Key InChIKey=FGSIISUYUSDDTO-UHFFFAOYSA-N
Data 2 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 511377
TargetBromodomain-containing protein 4 [49-170](Homo sapiens (Human))
Board of Regents, The University of Texas System
US Patent
Board of Regents, The University of Texas System
US Patent
Affinity DataIC50: 1.35E+4nMAssay Description:The binding of 2.5 nM of BRD4(49-170) to 10 nM biotin-H4(1-21) Ac-K5/8/12/16 (AnaSpec. 64989) was assessed following the same procedure described for...More data for this Ligand-Target Pair
TargetCREB-binding protein [1081-1197](Homo sapiens (Human))
Board of Regents, The University of Texas System
US Patent
Board of Regents, The University of Texas System
US Patent
Affinity DataIC50: 1nMAssay Description:5 nM GST-CBP(1081-1197) and 20 nM biotin-H4(1-21) Ac-K5/8/12/16 (AnaSpec. 64989) were incubated with varying concentrations of CBP inhibitors in 15 &...More data for this Ligand-Target Pair