BDBM511377 3-(4,4- difluorocyclohexyl)-N- methyl-1-(2-(1-methyl- 1H-pyrazol-4-yl)-3- (trifluoromethyl)quinolin- 5-yl)-5,6- dihydroimidazo[1,5- a]pyrazine-7(8H)- carboxamide::US11058688, Example 78

SMILES CNC(=O)N1CCn2c(C1)c(nc2C1CCC(F)(F)CC1)-c1cccc2nc(-c3cnn(C)c3)c(cc12)C(F)(F)F

InChI Key InChIKey=FGSIISUYUSDDTO-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 511377   

TargetBromodomain-containing protein 4 [49-170](Homo sapiens (Human))
Board of Regents, The University of Texas System

US Patent
LigandPNGBDBM511377(3-(4,4- difluorocyclohexyl)-N- methyl-1-(2-(1-meth...)
Affinity DataIC50:  1.35E+4nMAssay Description:The binding of 2.5 nM of BRD4(49-170) to 10 nM biotin-H4(1-21) Ac-K5/8/12/16 (AnaSpec. 64989) was assessed following the same procedure described for...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCREB-binding protein [1081-1197](Homo sapiens (Human))
Board of Regents, The University of Texas System

US Patent
LigandPNGBDBM511377(3-(4,4- difluorocyclohexyl)-N- methyl-1-(2-(1-meth...)
Affinity DataIC50:  1nMAssay Description:5 nM GST-CBP(1081-1197) and 20 nM biotin-H4(1-21) Ac-K5/8/12/16 (AnaSpec. 64989) were incubated with varying concentrations of CBP inhibitors in 15 &...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent