BDBM511578 US11059794, Example 6.38::tert-butyl 4-[2-(5- sulfamoylthiophen-2- yl)sulfonylethyl]piperidine-1- carboxylate (intermediate 15.4)/3- [2-[(5-methyltetrazol-2-yl)methyl]- 4- (trifluoromethyl)phenyl]propanoic acid (CAS-RN 1646783-83-6)
SMILES Cc1nnn(Cc2cc(ccc2CCC(=O)N2CCC(CCS(=O)(=O)c3ccc(s3)S(N)(=O)=O)CC2)C(F)(F)F)n1
InChI Key InChIKey=REHYZYIYLUIPNH-UHFFFAOYSA-N
Data 2 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 511578
Affinity DataIC50: 7.30nMAssay Description:Human carbonic anhydrase II (hCA-II) inhibition was measured by an absorbance method using 4-nitrophenyl acetate (4-NPA) as its substrate. 4-NPA can ...More data for this Ligand-Target Pair
Affinity DataIC50: 1nMAssay Description:ATX inhibition was measured by a fluorescence quenching assay using a specifically labeled substrate analogue (MR121 substrate). To obtain this MR121...More data for this Ligand-Target Pair