BDBM511579 US11059794, Example 6.39::tert-butyl 4-(3-fluoro-5- sulfamoylpyridin-2- yl)sulfanylpiperidine-1-carboxylate (intermediate 9.1)/3-[2-[(5- methyltetrazol-2-yl)methyl]-4- (trifluoromethyl)phenyl]propanoic acid (CAS-RN 1646783-83-6)

SMILES Cc1nnn(Cc2cc(ccc2CCC(=O)N2CCC(CC2)Sc2ncc(cc2F)S(N)(=O)=O)C(F)(F)F)n1

InChI Key InChIKey=YMDDSFMLTGLUOI-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 511579   

TargetCarbonic anhydrase 2(Homo sapiens (Human))
Hoffmann-La Roche

US Patent
LigandPNGBDBM511579(US11059794, Example 6.39 | tert-butyl 4-(3-fluoro-...)
Affinity DataIC50:  8nMAssay Description:Human carbonic anhydrase II (hCA-II) inhibition was measured by an absorbance method using 4-nitrophenyl acetate (4-NPA) as its substrate. 4-NPA can ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetAtaxin-1(Homo sapiens (Human))
Hoffmann-La Roche

US Patent
LigandPNGBDBM511579(US11059794, Example 6.39 | tert-butyl 4-(3-fluoro-...)
Affinity DataIC50:  1nMAssay Description:ATX inhibition was measured by a fluorescence quenching assay using a specifically labeled substrate analogue (MR121 substrate). To obtain this MR121...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent