BDBM511621 US11059801, Compound dBET29

SMILES Cc1sc-2c(c1C)C(=N[C@@H](CC(=O)NCCCCCCOc1cccc3C(=O)N(C4CCC(=O)NC4=O)C(=O)c13)c1nnc(C)n-21)c1ccc(Cl)cc1

InChI Key InChIKey=IWIUHSRVMHYMOY-QBHOUYDASA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 511621   

TargetDNA damage-binding protein 1/Protein cereblon(Homo sapiens (Human))
Dana-Farber Cancer Institute

US Patent
LigandPNGBDBM511621(US11059801, Compound dBET29)
Affinity DataIC50:  6.05nMAssay Description:A thalidomide competition AlphaScreen assay was employed to measure the binding affinity (IC50) of thalidomide conjugates and novel IMiDs to CRBN-DDB...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent