BDBM512913 US11091444, Compound FAH-3::US11142505, FAH #3
SMILES CN1C(N)=NC(C1=O)(c1ccc(OC(F)F)c(C)c1)c1cc(F)cc(F)c1
InChI Key InChIKey=GDKGAYIPAAQPCP-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 4 hits for monomerid = 512913
TargetAmyloid-beta precursor protein(Homo sapiens (Human))
Buck Institute For Research On Aging
US Patent
Buck Institute For Research On Aging
US Patent
Affinity DataIC50: 520nMAssay Description:β-sectretase inhibitor IV from Calbiochem (cat #565788).More data for this Ligand-Target Pair
Affinity DataIC50: 710nMAssay Description:Approximately 200 nM to 10 μM substrate, approximately 10 to 200 pM enzyme, and approximately 0.1 nM to 10 μM of the agent(s), in aqueous s...More data for this Ligand-Target Pair
Affinity DataIC50: 530nMAssay Description:Approximately 200 nM to 10 μM substrate, approximately 10 to 200 pM enzyme, and approximately 0.1 nM to 10 μM of the agent(s), in aqueous s...More data for this Ligand-Target Pair
TargetAmyloid-beta precursor protein(Homo sapiens (Human))
Buck Institute For Research On Aging
US Patent
Buck Institute For Research On Aging
US Patent
Affinity DataKd: 300nMAssay Description:β-sectretase inhibitor IV from Calbiochem (cat #565788).More data for this Ligand-Target Pair