BDBM51308 4-(2-furanyl)-6-(4-methylphenyl)-2-oxo-1H-pyridine-3-carbonitrile::4-(2-furyl)-2-keto-6-(p-tolyl)-1H-pyridine-3-carbonitrile::4-(2-furyl)-6-(4-methylphenyl)-2-oxo-1,2-dihydro-3-pyridinecarbonitrile::4-(furan-2-yl)-6-(4-methylphenyl)-2-oxidanylidene-1H-pyridine-3-carbonitrile::4-(furan-2-yl)-6-(4-methylphenyl)-2-oxo-1H-pyridine-3-carbonitrile::MLS000850476::SMR000456494::cid_368866

SMILES Cc1ccc(cc1)-c1cc(-c2ccco2)c(C#N)c(=O)[nH]1

InChI Key InChIKey=DZDATXSRPCXDQF-UHFFFAOYSA-N

Data  5 IC50  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 51308   

TargetPOsterior Segregation(Caenorhabditis elegans)
Broad Institute

Curated by PubChem BioAssay
LigandPNGBDBM51308(4-(2-furanyl)-6-(4-methylphenyl)-2-oxo-1H-pyridine...)
Affinity DataEC50:  2.61E+4nMAssay Description:Broad Institute: MLPCN maternal gene expression Project ID: 2024 Keywords: Zinc finger, C. elegans, maternal gene expression, RNA-protein interac...More data for this Ligand-Target Pair
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TargetZinc finger protein mex-5(Caenorhabditis elegans)
Broad Institute

Curated by PubChem BioAssay
LigandPNGBDBM51308(4-(2-furanyl)-6-(4-methylphenyl)-2-oxo-1H-pyridine...)
Affinity DataEC50:  8.36E+3nMAssay Description:Broad Institute: MLPCN maternal gene expression Project ID: 2024 Keywords: Zinc finger, C. elegans, maternal gene expression, RNA-protein interac...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetGlycoprotein 42(Human herpesvirus 4 type 2)
Emory University

Curated by PubChem BioAssay
LigandPNGBDBM51308(4-(2-furanyl)-6-(4-methylphenyl)-2-oxo-1H-pyridine...)
Affinity DataIC50:  5.40E+4nMAssay Description:NIH Molecular Libraries Screening Centers Network [MLSCN] Emory Chemical Biology Discovery Center in MLSCN Assay provider: Theodore Jardetzky; Northw...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetLow molecular weight phosphotyrosine protein phosphatase(Homo sapiens (Human))
Burnham Center For Chemical Genomics

Curated by PubChem BioAssay
LigandPNGBDBM51308(4-(2-furanyl)-6-(4-methylphenyl)-2-oxo-1H-pyridine...)
Affinity DataIC50: >8.00E+4nMMore data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetBcl-2-like protein 1(Homo sapiens (Human))
The Scripps Research Institute Molecular Screening Center

Curated by PubChem BioAssay
LigandPNGBDBM51308(4-(2-furanyl)-6-(4-methylphenyl)-2-oxo-1H-pyridine...)
Affinity DataIC50:  1.09E+5nMAssay Description:Source (MLPCN Center Name): The Scripps Research Institute Molecular Screening Center Affiliation: The Scripps Research Institute, TSRI Assay Provide...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetLow molecular weight phosphotyrosine protein phosphatase(Homo sapiens (Human))
Burnham Center For Chemical Genomics

Curated by PubChem BioAssay
LigandPNGBDBM51308(4-(2-furanyl)-6-(4-methylphenyl)-2-oxo-1H-pyridine...)
Affinity DataIC50:  4.92E+4nMMore data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetInduced myeloid leukemia cell differentiation protein Mcl-1(Homo sapiens (Human))
The Scripps Research Institute Molecular Screening Center

Curated by PubChem BioAssay
LigandPNGBDBM51308(4-(2-furanyl)-6-(4-methylphenyl)-2-oxo-1H-pyridine...)
Affinity DataIC50: >1.21E+4nMAssay Description:Source (MLPCN Center Name): The Scripps Research Institute Molecular Screening Center Affiliation: The Scripps Research Institute, TSRI Assay Provide...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay