BDBM513470 US11091482, Compound I-25

SMILES CC(C)(C)c1onc(c1C(=O)O[C@@H]1C[C@@H]2CC[C@H](C1)N2c1nc2c(F)cc(cc2s1)C(O)=O)-c1c(Cl)cccc1Cl

InChI Key InChIKey=NUFDJXVTOLMXFV-ZSHCYNCHSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 513470   

TargetBile acid receptor(Homo sapiens (Human))
Ardelyx

US Patent
LigandPNGBDBM513470(US11091482, Compound I-25)
Affinity DataEC50:  63.1nMAssay Description:The affinity of FXR ligands for the ligand binding domain of FXR was determined using a commercially available human FXR ligand binding assay (Lantha...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent