BDBM513502 US11091482, Compound I-48

SMILES Clc1cccc(Cl)c1-c1noc(C2CC2)c1C(=O)O[C@@H]1C[C@@H]2CC[C@H](C1)N2c1ccc(cc1)C(=O)NS(=O)(=O)C1CC1

InChI Key InChIKey=RUVUTTFPSGAWEW-AERCQKQUSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 513502   

TargetBile acid receptor(Homo sapiens (Human))
Ardelyx

US Patent
LigandPNGBDBM513502(US11091482, Compound I-48)
Affinity DataEC50:  6.31nMAssay Description:The affinity of FXR ligands for the ligand binding domain of FXR was determined using a commercially available human FXR ligand binding assay (Lantha...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent