BDBM513667 US11091495, Example 169::US11091495, Example 228::US11091495, Example 28::US11091495, Example 78::US11091495, Example 86::US11220509, Example 169::US11485738, Example 86

SMILES Cc1cc(-c2cnc(NCc3c4CCOc4ccc3F)n3cc(nc23)C#N)n(C)n1

InChI Key InChIKey=WUFADHRATSOXBZ-UHFFFAOYSA-N

Data  13 IC50

PDB links: 1 PDB ID matches this monomer.

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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 13 hits for monomerid = 513667   

LigandPNGBDBM513667(US11091495, Example 169 | US11091495, Example 228 ...)
Affinity DataIC50: <100nMAssay Description:Briefly, compounds of the present invention were solubilized in DMSO and a series of 10, three-fold serial dilutions were made for each compound in 1...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
LigandPNGBDBM513667(US11091495, Example 169 | US11091495, Example 228 ...)
Affinity DataIC50: >500nMAssay Description:Briefly, compounds of the present invention were solubilized in DMSO and a series of 10, three-fold serial dilutions were made for each compound in 1...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
LigandPNGBDBM513667(US11091495, Example 169 | US11091495, Example 228 ...)
Affinity DataIC50: <100nMAssay Description:Briefly, compounds of the present invention were solubilized in DMSO and a series of 10, three-fold serial dilutions were made for each compound in 1...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
LigandPNGBDBM513667(US11091495, Example 169 | US11091495, Example 228 ...)
Affinity DataIC50: <100nMAssay Description:Briefly, compounds of the present invention were solubilized in DMSO and a series of 10, three-fold serial dilutions were made for each compound in 1...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
LigandPNGBDBM513667(US11091495, Example 169 | US11091495, Example 228 ...)
Affinity DataIC50:  300nMAssay Description:Briefly, compounds of the present invention were solubilized in DMSO and a series of 10, three-fold serial dilutions were made for each compound in 1...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
LigandPNGBDBM513667(US11091495, Example 169 | US11091495, Example 228 ...)
Affinity DataIC50: <100nMAssay Description:An aliquot of each serial dilution of test compound was added to deep 384 well plate using Acoustic Technology instrument (Echo 550, LabCyte) contain...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
LigandPNGBDBM513667(US11091495, Example 169 | US11091495, Example 228 ...)
Affinity DataIC50: <100nMAssay Description:Briefly, compounds of the present invention were solubilized in DMSO and a series of 10, three-fold serial dilutions were made for each compound in 1...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
LigandPNGBDBM513667(US11091495, Example 169 | US11091495, Example 228 ...)
Affinity DataIC50: <100nMAssay Description:Briefly, compounds of the present invention were solubilized in DMSO and a series of 10, three-fold serial dilutions were made for each compound in 1...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
LigandPNGBDBM513667(US11091495, Example 169 | US11091495, Example 228 ...)
Affinity DataIC50: <100nMAssay Description:Briefly, compounds of the present invention were solubilized in DMSO and a series of 10, three-fold serial dilutions were made for each compound in 1...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
LigandPNGBDBM513667(US11091495, Example 169 | US11091495, Example 228 ...)
Affinity DataIC50:  300nMAssay Description:Briefly, compounds of the present invention were solubilized in DMSO and a series of 10, three-fold serial dilutions were made for each compound in 1...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
LigandPNGBDBM513667(US11091495, Example 169 | US11091495, Example 228 ...)
Affinity DataIC50: <100nMAssay Description:Briefly, compounds of the present invention were solubilized in DMSO and a series of 10, three-fold serial dilutions were made for each compound in 1...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
LigandPNGBDBM513667(US11091495, Example 169 | US11091495, Example 228 ...)
Affinity DataIC50: <100nMAssay Description:Briefly, compounds of the present invention were solubilized in DMSO and a series of 10, three-fold serial dilutions were made for each compound in 1...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
LigandPNGBDBM513667(US11091495, Example 169 | US11091495, Example 228 ...)
Affinity DataIC50: <100nMAssay Description:An aliquot of each serial dilution of test compound was added to deep 384 well plate using Acoustic Technology instrument (Echo 550, LabCyte) contain...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB