BDBM515515 US11098063, Example 51
SMILES CCc1ocnc1C(=O)N1C2CCC1CN(Cc1c(nc3ncccn13)-c1ccc(Cl)cc1)C2
InChI Key InChIKey=UVWUDBXLAOOGPT-UHFFFAOYSA-N
Data 4 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 4 hits for monomerid = 515515
Affinity DataIC50: 21.7nMAssay Description:Table 1: In Vitro Electrophysiological Analysis of the Human TASK-1 and TASK-3 Channels Via Two-Electrode Voltage Clamp Technique in Xenopus laevis O...More data for this Ligand-Target Pair
Affinity DataIC50: 8.70nMAssay Description:The investigations on the inhibition of the recombinant TASK-1 and TASK-3 channels were conducted using stably transfected CHO cells. The compounds a...More data for this Ligand-Target Pair
Affinity DataIC50: 250nMAssay Description:Table 1: In Vitro Electrophysiological Analysis of the Human TASK-1 and TASK-3 Channels Via Two-Electrode Voltage Clamp Technique in Xenopus laevis O...More data for this Ligand-Target Pair
Affinity DataIC50: 35.9nMAssay Description:The investigations on the inhibition of the recombinant TASK-1 and TASK-3 channels were conducted using stably transfected CHO cells. The compounds a...More data for this Ligand-Target Pair