BDBM517319 3-[3- (difluoromethoxy)phenyl]- N-(1,1- dioxidotetrahydrothiophen- 3-yl)-1-(4-fluorophenyl)- 1H-indazole-6-carboxamide (enantiomer A)::US11104690, Example 136-A

SMILES FC(F)Oc1cccc(c1)-c1nn(-c2ccc(F)cc2)c2cc(ccc12)C(=O)N[C@@H]1CCS(=O)(=O)C1

InChI Key InChIKey=KBZAOZKBBKIYEP-GOSISDBHSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 517319   

TargetDiacylglycerol O-acyltransferase 2(Homo sapiens (Human))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM517319(3-[3- (difluoromethoxy)phenyl]- N-(1,1- dioxidotet...)
Affinity DataIC50:  1.40nMAssay Description:DGAT2 activity was determined by measuring the amount of enzymatic product triolein (1,2,3-Tri(cis-9-octadecenoyl)glycerol) using the membrane prep m...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent