BDBM518410 (2S,3R)-1-[4-[1-(Azetidin-3-yl)pyrazol-4-yl]-6-(trifluoromethyl)pyrimidin-2-yl]-2-methyl-azetidin-3-ol::US11124500, Example 4
SMILES C[C@H]1[C@H](O)CN1c1nc(cc(n1)C(F)(F)F)-c1cnn(c1)C1CNC1
InChI Key InChIKey=QKGCQHXUGXQHBD-QPUJVOFHSA-N
Data 2 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 518410
Affinity DataIC50: 11.4nMAssay Description:The intrinsic potency for inhibition of KHK C or A activity may be measured using an enzymatic assay which measures the production of FIP. Compounds ...More data for this Ligand-Target Pair
Affinity DataIC50: 14.4nMAssay Description:The intrinsic potency for inhibition of KHK C or A activity may be measured using an enzymatic assay which measures the production of FIP. Compounds ...More data for this Ligand-Target Pair