BDBM518419 2-[(2S)-2-Methylazetidin-1-yl]-4-[1-(4-piperidyl)pyrazol-4-yl]-6-(trifluoromethyl)pyrimidine::US11124500, Example 13

SMILES C[C@H]1CCN1c1nc(cc(n1)C(F)(F)F)-c1cnn(c1)C1CCNCC1

InChI Key InChIKey=INRNILCXHRZIOZ-NSHDSACASA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 518419   

TargetIsoform A of Ketohexokinase (Peripheral)(Homo sapiens (Human))
Eli Lilly

US Patent
LigandPNGBDBM518419(2-[(2S)-2-Methylazetidin-1-yl]-4-[1-(4-piperidyl)p...)
Affinity DataIC50:  7.69nMAssay Description:The intrinsic potency for inhibition of KHK C or A activity may be measured using an enzymatic assay which measures the production of FIP. Compounds ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetKetohexokinase(Homo sapiens (Human))
Eli Lilly

US Patent
LigandPNGBDBM518419(2-[(2S)-2-Methylazetidin-1-yl]-4-[1-(4-piperidyl)p...)
Affinity DataIC50:  15.5nMAssay Description:The intrinsic potency for inhibition of KHK C or A activity may be measured using an enzymatic assay which measures the production of FIP. Compounds ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent