BDBM518428 6-[1-[2-[(3R,4R)-3,4- Dihydroxypyrrolidin-1-yl]-2-oxo- ethyl]pyrazol-4-yl]-2-[(2S)-2- methylazetidin-1-yl]-4- (trifluoromethyl)pyridine-3- carbonitrile::US11124500, Example 22
SMILES C[C@H]1CCN1c1nc(cc(c1C#N)C(F)(F)F)-c1cnn(CC(=O)N2C[C@@H](O)[C@H](O)C2)c1
InChI Key InChIKey=FZDYDDBXXVCRTR-YMRXKLBXSA-N
Data 2 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 518428
Affinity DataIC50: 33.7nMAssay Description:The intrinsic potency for inhibition of KHK C or A activity may be measured using an enzymatic assay which measures the production of FIP. Compounds ...More data for this Ligand-Target Pair
Affinity DataIC50: 61.3nMAssay Description:The intrinsic potency for inhibition of KHK C or A activity may be measured using an enzymatic assay which measures the production of FIP. Compounds ...More data for this Ligand-Target Pair