BDBM518439 1-(3,3-Dimethylpiperazin-1-yl)-2-[4-[2- [(2S)-2-methylazetidin-1-yl]-6- (trifluoromethyl)pyrimidin-4-yl]pyrazol- 1-yl]ethanone::US11124500, Example 31
SMILES C[C@H]1CCN1c1nc(cc(n1)C(F)(F)F)-c1cnn(CC(=O)N2CCNC(C)(C)C2)c1
InChI Key InChIKey=BLDCIJWRIGRMIF-ZDUSSCGKSA-N
Data 2 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 518439
Affinity DataIC50: 70.5nMAssay Description:The intrinsic potency for inhibition of KHK C or A activity may be measured using an enzymatic assay which measures the production of FIP. Compounds ...More data for this Ligand-Target Pair
Affinity DataIC50: 34.7nMAssay Description:The intrinsic potency for inhibition of KHK C or A activity may be measured using an enzymatic assay which measures the production of FIP. Compounds ...More data for this Ligand-Target Pair