BDBM518859 US11160797, Example 2

SMILES COc1cc(cn(C(C)C)c1=O)-c1cncc(c1)-c1ccc2N(C)C(=O)Cc2c1

InChI Key InChIKey=LJUBHCPBQBKBHM-UHFFFAOYSA-N

Data  7 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 518859   

TargetActivin receptor type-1 [172-499](Homo sapiens (Human))
Novartis

US Patent
LigandPNGBDBM518859(US11160797, Example 2)
Affinity DataIC50:  87nMAssay Description:Example 53: The assays were performed in 384-well, low volume microtiter assay plates in a final reaction volume of 6 ul. Dose-response curves were g...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetBone morphogenetic protein receptor type-1A [198-525](Homo sapiens (Human))
Novartis

US Patent
LigandPNGBDBM518859(US11160797, Example 2)
Affinity DataIC50:  520nMAssay Description:Example 53: The assays were performed in 384-well, low volume microtiter assay plates in a final reaction volume of 6 ul. Dose-response curves were g...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetActivin receptor type-1 [172-499](Homo sapiens (Human))
Novartis

US Patent
LigandPNGBDBM518859(US11160797, Example 2)
Affinity DataIC50:  80nMAssay Description:Example 54:The assays were performed in 384-well, low volume microtiter assay plates in a final reaction volume of 9 ul. Dose-response curves were ge...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetBone morphogenetic protein receptor type-1B [168-495](Homo sapiens (Human))
Novartis

US Patent
LigandPNGBDBM518859(US11160797, Example 2)
Affinity DataIC50:  940nMAssay Description:Example 54:The assays were performed in 384-well, low volume microtiter assay plates in a final reaction volume of 9 ul. Dose-response curves were ge...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSerine/threonine-protein kinase receptor R3 [166-493](Homo sapiens (Human))
Novartis

US Patent
LigandPNGBDBM518859(US11160797, Example 2)
Affinity DataIC50:  410nMAssay Description:Example 54:The assays were performed in 384-well, low volume microtiter assay plates in a final reaction volume of 9 ul. Dose-response curves were ge...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTGF-beta receptor type-1 [162-503](Homo sapiens (Human))
Novartis

US Patent
LigandPNGBDBM518859(US11160797, Example 2)
Affinity DataIC50:  610nMAssay Description:Example 54:The assays were performed in 384-well, low volume microtiter assay plates in a final reaction volume of 9 ul. Dose-response curves were ge...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetActivin receptor type-1 [172-499,R206H](Homo sapiens (Human))
Novartis

US Patent
LigandPNGBDBM518859(US11160797, Example 2)
Affinity DataIC50:  60nMAssay Description:Example 54:The assays were performed in 384-well, low volume microtiter assay plates in a final reaction volume of 9 ul. Dose-response curves were ge...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent