BDBM519419 (4S,5R)-5-(3,5-bis(trifluoromethyl)phenyl)-3-(3-(isoquinolin-4-yl)propanoyl)-4-methyloxazolidin-2-one::US11141410, Example 65

SMILES C[C@H]1[C@H](OC(=O)N1C(=O)CCc1cncc2ccccc12)c1cc(cc(c1)C(F)(F)F)C(F)(F)F

InChI Key InChIKey=XWMRKUPNQVITEC-ZSEKCTLFSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 519419   

TargetN-acetylglucosamine-1-phosphotransferase subunits alpha/beta(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM519419((4S,5R)-5-(3,5-bis(trifluoromethyl)phenyl)-3-(3-(i...)
Affinity DataIC50:  10nMAssay Description:The TarO biochemical enzymatic assay is a liquid chromatography-mass spectroscopy (LC-MS) based end point assay that measures C55-P-P-GlcNAc (LIPID I...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent