BDBM519437 (4S,5R)-5-[3,5- bis(trifluoromethyl) phenyl]-4-ethyl-3- (3-isoquinolin- 4-ylpropanoyl)-1,3- oxazolidin-2-one::US11141410, Example 83

SMILES CC[C@H]1[C@H](OC(=O)N1C(=O)CCc1cncc2ccccc12)c1cc(cc(c1)C(F)(F)F)C(F)(F)F

InChI Key InChIKey=IUEYVOCGRCAGEN-RBBKRZOGSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 519437   

TargetN-acetylglucosamine-1-phosphotransferase subunits alpha/beta(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM519437((4S,5R)-5-[3,5- bis(trifluoromethyl) phenyl]-4-eth...)
Affinity DataIC50:  60nMAssay Description:The TarO biochemical enzymatic assay is a liquid chromatography-mass spectroscopy (LC-MS) based end point assay that measures C55-P-P-GlcNAc (LIPID I...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent