BDBM520628 1-methyl-5-(2'-((4-methylpiperazin-1-yl)methyl)-[1,1'-biphenyl]-4-yl)-3a,7a- dihydro-1H-benzo[d][1,2,3]triazole-7-carboxylic acid;::US11147801, Compound 29

SMILES CN1N=NC2C=C(C=C(C12)C(O)=O)c1ccc(cc1)-c1ccccc1CN1CCN(C)CC1

InChI Key InChIKey=NSYAALBYJSUJTC-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 520628   

TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Homo sapiens (Human))
Aurigene Discovery Technologies

US Patent
LigandPNGBDBM520628(1-methyl-5-(2'-((4-methylpiperazin-1-yl)methyl)-[1...)
Affinity DataIC50:  550nMAssay Description:The DHODH activity assay is a coupled enzyme assay in which oxidation of DHO and subsequent reduction of ubiquinone are stoichiometrically equivalent...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent