BDBM521444 N-(1-(1-((5- Chlorobenzo [b]thiophen- 2-yl)methyl)- 1,8-diazaspiro [4.5]decane-8- carbonyl)-1H- pyrazol-3- yl)acetamide::US11149037, Example 39

SMILES CC(=O)Nc1ccn(n1)C(=O)N1CCC2(CCCN2Cc2cc3cc(Cl)ccc3s2)CC1

InChI Key InChIKey=CXOQPUIRGKGXQP-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 521444   

TargetFatty-acid amide hydrolase 1(Homo sapiens (Human))
H. Lundbeck

US Patent
LigandPNGBDBM521444(N-(1-(1-((5- Chlorobenzo [b]thiophen- 2-yl)methyl)...)
Affinity DataIC50:  5.50E+3nMAssay Description:Proteomes (mouse brain membrane fraction or cell lysates for mouse assays; human prefrontal cortex or PC3 cell membrane fractions for human assays) (...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMonoglyceride lipase(Homo sapiens (Human))
H. Lundbeck

US Patent
LigandPNGBDBM521444(N-(1-(1-((5- Chlorobenzo [b]thiophen- 2-yl)methyl)...)
Affinity DataIC50: <100nMAssay Description:Proteomes (mouse brain membrane fraction or cell lysates for mouse assays; human prefrontal cortex or PC3 cell membrane fractions for human assays) (...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent